Acyl bromides
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 5mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
![eMolecules 7789-45-9 | Copper(II) bromide | Chem-Impex | MFCD00010970 | 223.354 | Br2Cu | 98.000 | [Cu++].[Br-].[Br-] | 100g | 272388320](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000160426.jpg-250.jpg)
eMolecules 7789-45-9 | Copper(II) bromide | Chem-Impex | MFCD00010970 | 223.354 | Br2Cu | 98.000 | [Cu++].[Br-].[Br-] | 100g | 272388320
Copper(II) bromide | Chem-Impex | 7789-45-9 | MFCD00010970 | 223.354 | Br2Cu | 98.000 | [Cu++].[Br-].[Br-] | 100g | 272388320
![Medchemexpress LLC Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 13-[(2-fluorophenyl)methyl]-5,6-dihydro-9,10-dimethoxy- | 1390654-28-0 | 98.8% | 524.38 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000437181-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 13-[(2-fluorophenyl)methyl]-5,6-dihydro-9,10-dimethoxy- | 1390654-28-0 | 98.8% | 524.38 | 10 MG
Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 13-[(2-fluorophenyl)methyl]-5,6-dihydro-9,10-dimethoxy- | 1390654-28-0 | 98.8% | 524.38 | 10 MG
Medchemexpress LLC Rocuronium Bromide | 119302-91-9 | ≥95% | 609.68 | 100 MG
Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant. It is used in modern anaesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
- Reduced twitch tensions in normal and pretreated diaphragms in a concentration-dependent fashion.
- ED95 is similar for children and adults.
- Duration of action is similar to vecuronium, shorter for children than adults.
- Readily reversed with conventional doses of cholinesterase-inhibiting drugs.
- Facilitates endotracheal intubation.
- Provides skeletal muscle relaxation during surgery or mechanical ventilation.
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | 99.1% | 1 ML
Umeclidinium bromide 10 mM solution in DMSO is a potent muscarinic acetylcholine receptor antagonist provided for laboratory research use. The ready-to-use solution supports in vitro receptor pharmacology and biochemical assays.
- Provided as a 10 mM solution in DMSO.
- Volume: 1 mL.
- CAS number: 869113-09-7.
- Molecular formula: C29H34BrNO2.
- Molecular weight: 508.49 g·mol⁻¹.
- Target: muscarinic acetylcholine receptors (M1-M5).
- Reported Ki: 0.05-0.16 nM across M1-M5.
- Intended for research use only.
Medchemexpress LLC 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine | 51549-36-1 | 98.0% | 445.58 | 10 MM X 1 ML
5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside suitable for use in the synthesis of deoxyribonucleic acid or nucleic acid.
- Modified nucleoside for various research applications
- Purity of 98.0%
- Available as a white to off-white solid
- Stable under recommended storage conditions
- Soluble in DMSO at 250 mg/mL
Apexbio Technology LLC Otilonium Bromide 26095-59-0 10mM (in 1mL DMSO)
Otilonium Bromide (CAS 26095-59-0) is an orally-administered muscarinic acetylcholine receptor (mAChR) antagonist exhibiting smooth muscle relaxation properties Its mechanism involves inhibition of calcium mobilization within intestinal smooth muscle cells lowering intracellular free calcium levels and thus attenuating muscle contractile activity In research settings Otilonium Bromide is commonly employed to investigate pathophysiological processes in irritable bowel syndrome (IBS) and dysfunctions associated with intestinal smooth muscle motility
Medchemexpress LLC Tiotropium bromide | 136310-93-5 | 472.42 | 1 ML
Tiotropium bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. It is a 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. It improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
- Targets mAChR
- Involved in GPCR/G Protein and neuronal signaling pathways
- Long-acting, stops signaling between neurons and leads to muscle relaxation
- Used in the management of chronic obstructive pulmonary disease
- Improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure
eMolecules 1076199-21-7 | Ambeed | tert-Butyl (2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethyl)carbamate | 100mg | 552573626 | A138365 | MFCD09840081 | 356.257 | C13H26BrNO5
Ambeed | 2-Amino-3-bromobenzonitrile | 1g | 552746008 | A597346 | 114344-60-4 | MFCD05670539 | 197.035 | C7H5BrN2
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Medchemexpress LLC N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite | 179479-02-8 | 98.0% | C48H54N7O8P | 50 MG
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog primarily functioning as a smooth muscle vasodilator. It has also shown properties in inhibiting cancer progression, making it relevant for research in various disease areas.
- Acts as a smooth muscle vasodilator
- Inhibits cancer progression
- Useful in research for cancer, cardiovascular disease, and blood diseases
- For research use only
Medchemexpress LLC Ipratropium bromide hydrate | 66985-17-9 | 99.9% | 100 MG
Ipratropium bromide hydrate is a muscarinic receptor antagonist that relaxes smooth muscle. It is used in research for conditions such as COPD and asthma, acting with high potency on M1, M2, and M3 receptors. This product is intended for research use only.
- Muscarinic receptor antagonist
- Relaxes smooth muscle
- Effective in research for COPD and asthma
- High potency on M1, M2, and M3 receptors
Cayman Chemical N4-benzoyl-Cytidine, Purity: ≥98%, CAS: 13089-48-0, 250 g
A benzyolated derivative of cytidine; a substrate of UCK1 and UCK2; has been used in the synthesis of 2ʹ-OH protecting groups for solid-phase RNA synthesis and synthetic oligonucleotides for UV light-induced and targeted gene silencing in zebrafish embryos
Selleck Chemical LLC Pinaverium bromide
Pinaverium bromide (Icosapentaenoic acid) acts as a calcium channel blocker and is useful for functional gastrointestinal disorders
Medchemexpress LLC Otilonium bromide | 26095-59-0 | 99.7% | 25 MG
Otilonium bromide | 26095-59-0 | 99.7% | 25 MG